Our investigations

Prenatal diagnostics & ultrasound

We can do that for you.

We use the latest technology to detect abnormalities during pregnancy: With particularly high-resolution 3-D and 4-D ultrasound equipment, we can assess the risk of possible malformations and illnesses in the child at an early stage, and this technology also offers a high level of safety for you and your child. 

 

We would like to introduce you to these and other prenatal diagnostic procedures - invasive and non-invasive - that are used. Our aim is to provide informed patients with the best possible advice so that they can make their own decisions about which tests they would like to have carried out.

 

To give you a basis of knowledge, you will find a detailed description of each below.

Ultrasound diagnostics

For many years, we have been offering optimal ultrasound diagnostics with state-of-the-art equipment and professional qualifications.

 

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Chromosome testing from maternal blood - the Praenatest® from Lifekodexx - what do you need to know?

 

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First trimester screening

First of all: The vast majority of babies are healthy! Nevertheless, all women - regardless of their age - run a small risk of their baby being affected by a mental or physical illness.

 

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Precision diagnostics 

At 20-22 weeks of pregnancy, the baby is so large and the organs are so well developed that their structure and function can be assessed using this ultrasound scan. Facial features and facial expressions can often be visualised. Most malformations can be ruled out or recognised at this stage - this also applies to most heart defects. The sex of the child can also normally be recognised at this stage. 

 

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Fetal echocardiography

Congenital heart defects are among the most common malformations. They occur in 8 out of 1000 newborns. Most heart defects are serious in themselves, but they can also indicate other serious illnesses in the foetus. They therefore usually require specialised care of the newborn by paediatric cardiologists immediately after birth.

 

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Doppler examination

Doppler sonography (also known as growth ultrasound), a special ultrasound technique, is used to visualise and measure the blood flow in the mother and child.

 

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3D ultrasound/4D ultrasound

3-D/4-D sonography is the further development of the conventional two-dimensional ultrasound examination in prenatal diagnostics, whereby 3-D stands for a still image and 4-D for moving images.

 

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Invasive diagnostics

In addition to the various sonographies, there are also prenatal examination methods that involve a small intervention.

 

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Amniocentesis

The analysis of the amniotic fluid includes the examination of the chromosomes and the determination of the alpha-fetoprotein as standard.

 

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Chorionic villus sampling

The chorion is a layer of cells on the outside of the amniotic sac. The chorion cells develop into chorionic villi, which go on to form the foetal part of the placenta. Although these cells are not part of the unborn child, they are usually genetically identical.

 

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Publications

Bamberg C, Hocher B, Slowinksi T, Halle H, Hartung J Pregnancy on intesified dialysis: fetal surveillance and outcome. Fetal Diagn Ther 2006   

 

Hartung JKalache KD, Heyna C,Heling K-S, Kuhlig M, Wauer R, Bollmann R, Chaoui R. Outcome of 60 neonates who had ARED flow prenatally

compared to an amtched control group of appropriate-for-gestational age preterm neonates. Ultrasound Obstet Gynecol 2005; 25:

 

Hartung JKalache K, Chaoui R. The 3D power Doppler ultrasound in foetal diagnostics. Ultrasound in Medicine (European J Ultrasound) 2004; 25: 195 - 199

 

Hartung JMeckies J. Management of a case of uterine scar pregnancy treated by potassium injection. Ultrasound Obstet Gynecol 2003; 21 (1): 94 - 95 (LETTER)

 

Hartung JHeling K-S, Rake A, Zimmer C, Chaoui R. Aneurysm of the vein of Galen detected in a 22 weeks foetus by signs of volume overload. Prenatal Diagn 2003; 23: 901 - 903

 

Urban M and Hartung J. Ultrasonographic and clinical appearance of a 22-week-old fetus with Brachmann-de Lange syndrome. Am J Med Gen 2001; 102 (1): 73-75

 

Chaoui R, Kalache K, Hartung J. Application of three dimensional power Doppler ultrasound in prenatal diagnosis. Ultrasound Obstet Gynecol 2001; 17: 22-29

 

Hartung JChaoui R, Bollmann. Non-immune hydrops secondary to fetomaternal hemorrage treated by serial fetal intravscular transfusions. Obstet Gynecol 2000; 96 (5): 844

 

Hartung JChaoui R, Kalache K, Tennstedt C, Bollmann R. Prenatal diagnosis of intrahepatic communications of the umbilical vein with atypical arteries (av-fistulae)
in two cases of trisomy 21 using colour Doppler ultrasound. Ultrasound Obstet Gynecol 2000; 16 (3): 271 - 274

 

Hartung JChaoui R, Bollmann R. Amniotic fluid pressure in both cavities of twin - twin - transfusion syndrome. Fetal Diagn Ther 2000; 15 (2): 79-82

 

Hartung JEnders G, Chaoui R, Arents, Tennstedt C, Bollmann R. Prenatal Diagnosis of congenital varicella syndrome and detection of the varicella virus in the fetus.
Prenatal Diagn 1999; 19 (2): 163 - 166

 

Hartung JChaoui R. Ultrasound in pregnancy: a contribution to a gentle and safe birth. The Gynaecologist (1999) 1: 60 - 65

 

Hartung JChaoui R, Wauer R, Bollmann R. Fetal hepatosplenomegaly: an isolated sign of trisomy 21 in a case of myeloprolipherative disorder.
Ultrasound Obstet Gynecol 1998; 11 (6): 453 - 455

 

Heling KS, Tennstedt C, Chaoui R, Kalache KD, Hartung JBollmann R. Reliability of prenatal sonographic lung biometry in the diagnosis of pulmonary hypoplasia.
Prenat Diagn 2001 21(8):649-57.

 

Heling K-S, Chaoui R, Hartung JKirchmair F, Bollmann R. Prenatal diagnosis of congenital neuroblastoma. Fetal Diagn Ther 1999; 1: 47 - 52

 

Kalache KD, Chaoui R, Hartung JWernecke KD, Bollmann. Doppler assessment of tracheal fluid flow during fetal breathing movements in case of
congenital diaphragmatic hernia. Ultrasound Obstet Gynecol 1998; 12: 27 - 32

 

Chaoui R, Taddei F, Bast C, Lenz F, Kalache KD, Hartung JBollmann R. Sonographic examination of the foetal pulmonary circulation.
The Gynaecologist 1997; 30: 230-239

 

Lun A, Lenz F, Priem F, Brux B, Gross J, Bollamnn R, Hartung JBartho S, Kirchmeier F, Reisinger I. Biochemical diagnosis in prenatal uropathy.
Clin Biochem 1994; 27 (4): 283 287

 

Lenz F, Machlitt A, Hartung JBollmann R, Chaoui R. Fetal pulmonary venous flow pattern is determined by left atrial pressure: a report of two cases of left heart hypoplasia,
one with patent and the other with closed interatrial communication. Ultrasound Obstet Gynecol 2002; 19 (4): 392 - 395

 

Hartung JTetzner V. Detection of muscular septal defects using Power - Doppler Ultrasound in mid - trimester echocardiography and description of natural history.
Ultrasound Obstet Gynecol 2004; 24: 218

 

Hartung J, Heyna C, Kalache KD, Heling K-S, Kuhlig M, Wauer R, Chaoui R, Bollmann R. Progression and prognosis of 60 foetuses with ARED -
Flow between 24/0 and 34/0 weeks' gestation compared to a matched control group of preterm infants. Ultrasound in Medicine (European J Ultrasound) 2004; 562 - 563

 

Hartung JKalache KD, Heling K-S, Heyna C, Wauer R, Bollmann R, Chaoui R. Course and outcome of 60 foetuses with ARED-Flow between
24 and 34 weeks' gestation compared to a matched control group. Ultrasound Obstet Gynecol 2003, Volume 22, Issue S1,32

 

Hartung JChaoui, R, Lenz, F, Kalache, K, Bollmann, R. Malformations of the intraabdominal umbilical vein: prenatal detection using colour
Doppler and colour power (1999) Archives of Perinatal Medicine Vol. 5, Suppl. 1, 11 - 12

 

Hartung JHeling K-S, Rake A, Zimmer C, Chaoui R. Vein of Galen aneurysm detected at 22 weeks by cardiac signs of volume overload.
Ultrasound Obstet Gynecol 2002; 20:50

 

Hartung JChaoui, R, Kalache, K, Heling, K-S, Bollmann, R Abnormalities of the fetal umbilical vein: prenatal diagnosis and fetal outcome (1998)
Ultrasound Obstet Gynecol Vol. 12, Suppl. 1, 52

 

Hartung J, Kalache, K, Chaoui, R, Bollmann, R. Amniotic fluid pressure during amniograinage in twin - to - twin transfusion syndrome and polyhydramnios (1998)
Ultrasound in Obstet Gynecol Vol. 12, Suppl. 1, 147

 

Hartung JChaoui, R, Bollmann, R.Is amniotic fluid pressure useful in predictig outcome in twin - to - twin syndrome ?
(1996) Ultrasound Obstet Gynecol (1996) Vol. 8, Supl. 1, 141

 

Hartung JChaoui, R, Bollmann, R.Hepatosplenomegaly in the fetus - a further marker of trisomy 21 ? (1996) Ultrasound Obstet Gynecol Vol. 8, Supl. 1, 142

 

Chaoui, R, Kalache K. Heling K.-S., Hartung J, Bollmann R. Three - dimensional colour power angiography in the assessment of fetal cardiovascular anatomy
(1999) Archives of Perinatal Medicine Vol. 5, Suppl. 1, 7

 

Chaoui R, Kalache K. Heling K.-S., Hartung J, Bollmann R. Three - dimensional colour power angiography in the assessment of fetal cardiovascular anatomy
(1999) Archives of Perinatal Medicine Vol. 5, Suppl. 1, 7

 

Heling K.-S., Chaoui R. Hartung J, Kalache K, Bollmann R Perfusion through the foramen ovale in normal and in pregnancies complicated by IUGR and heart defects
(1999) Archives of Perinatal Medicine Vol. 5, Suppl. 1, 13

 

Lenz F, Chaoui R, Machlitt A, Hartung J, Heling K.S., Bollmann R Pulmonary venous flow in fetal cardiac anomalies (1999) Archives of Perinatal Medicine Vol. 5, Suppl. 1, 2

 

Heling, K-S, Chaoui, R, Hartung J, Kalache, K, Bollmann, R Hyperechogenic lung malformations of the foetus: Prenatal diagnosis and outcome in 29 fetuses (1999).
Z. Obstetr. Neonatol. Vol. 203, 86

 

Heling, K-S, Hartung JChaoui, R, Kirchmeir, F, Bollmann, R Prenatal diagnosis of foetal ileus (1999). Z. Obstetr. Neonatol. Vol. 203, 87

 

Heling, K-S, Chaoui, R, Hartung JKalache, K, Bollmann, R. Z. Perfusion of the foramen ovale in pregnancy (1999) Z. Geburtsh. Neonatol. Vol. 203, 87

 

Lenz, F, Chaoui, R, Machlitt, A, Hartung JBollmann, R. Doppler sonography of the pulmonary veins in foetal heart defects (1999) Z. Geburth. Neonatol. Vol. 203, 88

 

Kalache, K, Chaoui, R, Heling, K-S, Hartung J, Bollmann, R 3-D colour Doppler in obstetrics: a useful alternative to 3-D colour power angio
(1998) Ultrasound Obstet Gynecol Vol. 12, Supl. 1, 56

 

Heling, K-S, Hartung JChaoui, R, Kalache, K, Bollmann, R Natural history of 23 foetuses with hyperechogenic lung lesions (1998). Ultrasound Obstet Gynecol Vol. 12, Supl. 1, 11

 

Heling, K-S, Chaoui, R, Hartung J, Kalache, K, Bollmann, R Fetal ovarian cyst - prenatal detection and postnatal outcome (1998) Ultrasound Obstet Gynecol Vol. 12, Supl. 1, 118

 

Heling, K-S, Chaoui, R, Hartung J, Kalache, K, Bollmann, R Biometry and Doppler values of the foramen ovale in the second half of pregnancy
(1998) Ultrasound Obstet Gynecol Vol. 12, Supl. 1, 134

 

Chaoui, R, Kalache, K, Hartung J, Heling, K-S, Bollmann, R 3- D colour Doppler angio (3-D CPA) of the umbilical vessels in normal and abnormal pregnancies
(1998) Ultrasound Obstet Gynecol Vol. 12, Supl. 1, 150

 

Hartung J, Tennstedt, C, Weidemeier, A, Bollmann, R. Oligohydramnios: sonographic differential diagnosis and prognosis
(1994), R. Pediatrics and Related Topics, 33 (4), 342 - 343